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A full-body CT protocol in resuscitated adults with out of hospital cardiac arrest (OHCA) more often - and more quickly - found the cause of arrest than standard of care CT but did not improve neurologically intact survival.

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Computed tomography (CT) after out-of-hospital cardiac arrest (OHCA) often identifies clinically important pathology such as the etiology of the arrest, traumatic injuries from resuscitation, and consequences from inadequate perfusion.

Source
Diagnostic yield of computed tomography after non-traumatic out-of-hospital cardiac arrest. Resuscitation. 2023 Aug;189:109898. doi: 10.1016/j.resuscitation.2023.109898. Epub 2023 Jul 6.

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Clinically relevant bleeding events were more common after central venous catheter placement in patients with platelet counts of 10,000 to 50,000/mm³ who did not receive prophylactic platelet transfusion than those who did.

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In patients resuscitated after out-of-hospital cardiac arrest (OHCA), targeted mild hypercapnia was not associated with better neurologic outcomes at 6 months compared to normocapnia.

Source
Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest. N Engl J Med. 2023 Jun 15. doi: 10.1056/NEJMoa2214552. Epub ahead of print.

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Empiric macrolide therapy was associated with improved six and twelve-month survival among ICU patients with community-acquired pneumonia (CAP).

Source
Impact of macrolide treatment on long-term mortality in patients admitted to the ICU due to CAP: a targeted maximum likelihood estimation and survival analysis. Crit Care. 2023 May 31;27(1):212. doi: 10.1186/s13054-023-04466-x.

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Video laryngoscopy (VL) was associated with higher rates of first attempt intubation success compared to direct laryngoscopy (DL) for critically ill patients in the ICU and ED. Furthermore, use of VL was associated with better views of the glottis and was especially helpful for clinicians with less intubation experience.

Source
Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults [published online ahead of print, 2023 Jun 16]. N Engl J Med. 2023;10.1056/NEJMoa2301601. doi:10.1056/NEJMoa2301601

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The LUS-ARDS score can make a diagnosis of acute respiratory distress syndrome (ARDS) easier, particularly in patients who can’t have CT scan. The LUS-ARDS score performs similarly to the standard of care (Berlin criteria plus CXR evaluation) in diagnosis of ARDS in ventilated patients.

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Patients with septic shock on norepinephrine who were treated with fludrocortisone and hydrocortisone had an associated reduction of in-hospital death or discharge to hospice compared to those treated with hydrocortisone alone.

Source
Comparative Effectiveness of Fludrocortisone and Hydrocortisone vs Hydrocortisone Alone Among Patients With Septic Shock. JAMA Intern Med. 2023 Mar 27:e230258. doi: 10.1001/jamainternmed.2023.0258. Epub ahead of print.

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This retrospective study of thirty-three pediatric patients with severe traumatic brain injury (sTBI) demonstrated no increase in intracranial pressure (ICP) after administration of ketamine.

Source
Acute Effects of Ketamine on Intracranial Pressure in Children with Severe Traumatic Brain Injury. Crit Care Med. 2023 Feb 24; e005806 DOI: 10.1097

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Early identification and treatment of thoracic aortic dissection is paramount to patient survival and good clinical outcomes. Here's what you need to know.